Vasool Raja MBBS

Kamal Haasan

'Vasool Raja' Rajaraman Venkatraman

Prakash Raj

Dr. Vishwanathan

Prabhu

Vatti

Sneha

Janaki 'Paapu' Vishwanathan

Nagesh

Sriman Venkatraman

Rohini Hattangadi

Kasturi

Crazy Mohan

Professor Margabandhu

Karunas

Amit

Jayasurya

Zakir

Malavika

Priya

Ajay Rathnam

Medicine Professor

Kavithalaya Krishnan

Surgery Professor

Nithin Sathya

Neelakandan

Chitra Lakshmanan

Dr. Kalidas

Thalaivasal Vijay

Doctor

Santhana Bharathi

Gangadharan

Kaaka Radhakrishnan

Margabandhu's father

A. K. Veerasamy

Hospital cleaner

Madhan Bob

Mani Raja

Vaiyapuri

Piles Patient