Jesse James

Tyrone Power

Jesse Woodson James

Henry Fonda

Frank James

Nancy Kelly

Zerelda "Zee" Cobb

Randolph Scott

Marshall Will Wright

Henry Hull

Major Rufus Cobb

Slim Summerville

Jailer

J. Edward Bromberg

George Runyan

Brian Donlevy

Barshee

John Carradine

Bob Ford

Donald Meek

McCoy

Johnny Russell

Jesse James Jr.

Jane Darwell

Mrs. Samuels - Jesse's mother

Charles Tannen

Charles Ford

Claire Du Brey

Mrs. Bob Ford

Willard Robertson

Clarke

Harold Goodwin

Bill

Ernest Whitman

Pinkie

Eddy Waller

Deputy

Paul E. Burns

Hank

Spencer Charters

Minister